COMING SOON: Educational Guide for Healthcare Professionals

Yes. Clinical studies on Affron® show improvements in sleep quality, sleep latency (time to fall asleep), and restorative sleep — especially when stress or mood disturbances are contributing factors. It is clinically proven to help improve sleep quality in as little as 4 weeks.

No. Somnaffron™ is melatonin-free. It works by supporting mood balance and helping the body relax naturally, rather than acting as an external sleep hormone.

Yes. Affron® has multiple published human clinical trials supporting its benefits for sleep, stress and mood support. Research includes studies in adults as well as adolescents aged 12–16. It has a strong scientific foundation, with over 11 published human clinical studies to date.

Yes. Somnaffron™ is manufactured in Canada following strict quality and safety standards, and is Health Canada–approved with an assigned Natural Product Number (NPN).

Affron® is a high-quality, patented saffron extract made from 100% genuine Crocus sativus L. grown and manufactured in Spain.

Standardization ensures every batch delivers a reliable amount of the active compounds responsible for sleep, stress and mood support. Many generic saffron supplements vary widely in quality, meaning two bottles may not produce the same effects.

Current clinical research on Affron®, a standardized saffron extract, indicates that it is well-tolerated and does not cause significant side effects at typical doses used in human studies.

Human Clinical Trials

In a double-blind, placebo-controlled trial with healthy adults (doses: 22 mg/day and 28 mg/day for 4 weeks), Affron® supplementation did not result in any reported side effects. Participants experienced improved mood, reduced anxiety, and better stress management compared to placebo, with no adverse events noted.

https://www.sciencedirect.com/science/article/abs/pii/S0965229917300821?via%3Dihub 

Another randomized, double-blind, placebo-controlled study in adults with poor sleep (14 mg or 28 mg Affron® daily for 28 days) found no significant adverse effects. Saffron supplementation was well-tolerated, and no safety concerns were reported.

https://www.sciencedirect.com/science/article/abs/pii/S1389945721004330?via%3Dihub 

Consult a healthcare practitioner prior to use if you are taking antidepressants.

Do not use if you are taking blood thinners/anticoagulants or have a bleeding disorder.

Most saffron supplements use non-standardized or low-potency extracts, with inconsistent levels of active compounds.
Somnaffron® uses Affron®, which ensures:

• Consistent potency
• Clinically studied dosage
• High-purity extraction
• Proven benefits for mood, stress, and sleep support

This makes Somnaffron™ more reliable than generic saffron capsules.

Saffron is considered one of the most valuable ingredients in the world because it must be harvested entirely by hand. Each delicate stigma is picked individually, making the process incredibly labour-intensive and time-sensitive.

At ApothecaTree, we use Affron®, one of the most researched and clinically supported saffron extracts available. It costs significantly more than standard saffron extracts due to its guaranteed purity, traceable origin, and consistently measured active compounds.

Most generic saffron extracts lack these assurances. With Affron®, you can trust that every capsule delivers the proven support that make saffron truly exceptional.